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Table 2 Characteristics at baseline of patients in the training cohort

From: Establishment and validation of a prognosis nomogram for MIMIC-III patients with liver cirrhosis complicated with hepatic encephalopathy

Variable

Alive (n = 233)

Dead (n = 201)

P value

Demographics

 Age, year

53.51 (14.89)

56.40 (15.65)

0.016

 Gender, n(%)

  

0.674

  Men

143 (61.4)

134 (66.7)

 

  Women

90 (38.6)

67 (33.3)

 

 weight, kg

85.00 (25.00)

84.00 (26.00)

0.585

Etiology of cirrhosis(%)

  

0.896

 Alcoholic cirrhosis of liver

139 (59.7)

118 (58.7)

 

 Cirrhosis of liver without mention of alcohol

90 (38.6)

78 (38.8)

 

 Biliary cirrhosis

4 (1.7)

5 (2.5)

 

Firstday vital signs in ICUa

 Mean heart rate, beats/min

86.57 (22.44)

88.08 (24.61)

0.081

 MAP, mmHg

77.06 (15.90)

71.31 (11.99)

 < 0.001

 Mean respiratory rate, breaths/min

17.23 (5.21)

18.60 (5.18)

0.016

 Mean SpO2,%

98.00 (2.64)

97.40 (2.80)

0.002

 Mean temperature, °C

36.72 (0.80)

36.42 (0.76)

 < 0.001

Complication

 Alcohol abuse, n(%)

143 (61.4)

113 (56.2)

0.276

 Chronic pulmonary, n(%)

45 (19.3)

33 (16.4)

0.433

 Cardiac arrhythmias, n(%)

34 (14.6)

45 (22.4)

0.036

 Coagulopathy, n(%)

126 (54.1)

119 (59.2)

0.283

 Congestive heart failure, n(%)

36 (15.5)

32 (15.9)

0.893

 Diabetes, n(%)

59 (25.3)

64 (31.8)

0.133

 Hypertension, n(%)

78 (33.5)

71 (35.3)

0.686

 Renal failure, n(%)

41 (17.6)

42 (20.9)

0.384

First laboratory testsb

 Lactate, mmol/L

2.20 (1.30)

2.70 (2.15)

0.001

 ALT, IU/L

36.00 (32.00)

40.00 (48.00)

0.207

 Albumin, g/dL

2.80 (0.70)

2.70 (0.70)

0.041

 ALP, IU/L

123.00 (80.00)

128.00 (102.00)

0.272

 Anion gap, mEq/L

14.00 (6.00)

15.00 (6.00)

0.023

 AST, IU/L

69.00 (80.00)

75.00 (86.00)

0.168

 Bicarbonate, mEq/L

22.00 (7.00)

22.00 (7.00)

0.685

 Total bilirubin, mg/dL

3.60 (4.60)

5.50 (10.90)

 < 0.001

 Total calcium, mg/dL

8.30 (1.10)

8.40 (1.20)

0.183

 Chloride, mEq/L

103.00 (10.00)

101.00 (12.00)

0.002

 Creatinine, mg/dL

1.20 (1.40)

1.50 (1.50)

0.004

 Magnesium, mg/dL

1.90 (0.50)

2.00 (0.60)

0.014

 Potassium, mEq/L

4.10 (1.10)

4.40 (1.20)

0.021

 Sodium, mEq/L

137.00 (8.00)

134.00 (10.00)

0.002

 Urea Nitrogen, mg/dL

24.00 (30.00)

33.00 (30.00)

 < 0.001

 Hemoglobin, g/dL

10.20 (2.60)

10.40 (2.70)

0.641

 INR

1.70 (0.80)

1.90 (0.70)

0.005

 PLT, K/uL

100.00 (88.00)

102.00 (75.00)

0.750

 PT, sec

18.10 (5.40)

19.20 (6.50)

0.007

 PTT, sec

37.80 (11.60)

40.50 (14.20)

0.006

 RDW,%

17.10 (3.20)

17.90 (3.20)

0.002

 WBC, K/uL

8.00 (6.70)

9.10 (7.80)

0.015

 RBC, m/uL

3.13 (0.86)

3.17 (0.82)

0.639

Therapeutic measure

 Albumin use, n(%)

89 (38.2%)

122 (60.7%)

 < 0.001

 Furosemide use, n(%)

138 (59.2%)

94 (46.8%)

0.009

 PPI use, n(%)

185 (79.4%)

146 (72.6%)

0.099

 PAD, n(%)

104 (44.6%)

122 (60.7%)

0.001

Severity score

 SOFA

8.00 (4.00)

9.00 (5.00)

 < 0.001

 MELD

22.64 (11.65)

30.33 (11.32)

 < 0.001

Others

 Urine Outputc, ml

964.50 (1044.00)

1029.00 (1161.00)

 < 0.001

  1. Categorical variables were presented as frequency (percentage), parametric continuous variables were presented as median (interquartile)
  2. MAP Mean arterial pressure, SpO2 Blood oxygen saturation, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, INR International normalized ratio, PT Prothrombin time, PTT Partial thromboplastin time, PLT Platelet, RDW Red cell distribution width, WBC White blood cell count, RBC Red blood cell count, PPI.use Proton pump inhibitors use, PAD Percutaneous abdominal drainage, SOFA Sequential organ failure assessment, MELD Model for end-stage liver disease
  3. aVital signs were calculated as mean value during the first 24 h since ICU admission of each included patients
  4. bThe laboratory tests recorded the first value after admission
  5. cThe urine output was recorded during the first 24 h in the ICU
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BMC Gastroenterology

ISSN: 1471-230X

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