Combined use of CDAI and blood indices for assessing endoscopic activity in ileocolic Crohn’s disease

BMC Gastroenterology

Table 3 Median (95% CI) of AUC, cut-off value (in terms of the maximized Youden index) for identifying endoscopic activity in Training Cohort

Variable	AUC	95% CI	Cut-off value	P value
HB (g/L)	0.676	0.596–0.756	137.5	< 0.05
N (×10⁹/L)	0.603	0.521–0.685	4.14	< 0.05
L (×10⁹/L)	0.660	0.576–0.744	1.42	< 0.05
PLT (×10⁹/L)	0.682	0.605–0.759	236	< 0.05
CRP (mg/L)	0.826	0.764–0.888	6.1	< 0.05
ALB (g/L)	0.686	0.610–0.763	36.15	< 0.05
NLR	0.690	0.611–0.769	1.79	< 0.05
PLpR	0.735	0.663–0.807	10.16	< 0.05
PLT/ALB	0.712	0.636–0.789	6.0	< 0.05
CRP/ALB	0.827	0.765–0.888	0.09	< 0.05
CDAI	0.769	0.698–0.841	101.5	< 0.05

HB: hemoglobin; N: neutrophil; L: lymphocyte; PLT: platelet; CRP: C-reactive protein; ALB: albumin; NLR: neutrophil-to-lymphocyte ratio; PLpR: platelet-to-lymphocyte percentage ratio; CDAI: Crohn’s disease activity index

ISSN: 1471-230X