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Table 1 characteristics of patients in the model group and the validation group

From: Risk assessment of rectal anastomotic leakage (RAREAL) after DIXON in non-emergency patients with rectal cancer

Factors

Model (n = 323)

Validation (n = 150)

P

 

Patient related factors

 

Age(years, \(\stackrel{-}{x}\pm s\))

59.5 ± 11.6

59.3 ± 10.8

0.829

 

Gender, n = No (%)

  

0.442

 

 Female

111(34.4%)

57(38.0%)

  

 Male

212(65.6%)

93(62.0%)

  

AL

  

0.483

 

 Yes

26(8.0%)

15(10.0%)

  

 No

297(92.0%)

135(90.0%)

  

Smoking, n = No (%)

  

0.201

 

 Yes

85(26.3%)

48(32.0%)

  

 No

238(73.7%)

102(68.0%)

  

Alcohol excess, n = No (%)

  

0.296

 

 Yes

76(23.5%)

42(28.0%)

  

 No

247(76.5%)

108(72.0%)

  

Previous history of malignancy, n = No (%)

  

0.704

 

 Yes

37(11.5%)

19(12.7%)

 

 No

286(88.5%)

131(87.3%)

 

BMI(kg/m2, \(\stackrel{-}{x}\pm s\))

22.5 ± 2.7

22.8 ± 2.6

0.335

 

HbA1c, n = No (%)

    

 ≤ 6.3%

304(94.1%)

141(94.0%)

0.960

 

 > 6.3%

19(5.9%)

9(6.0%)

  

Diabetes mellitus, n = No (%)

  

0.936

 

 Yes

70(21.7%)

33(22.0%)

  

 No

253(78.3%)

117(78.0%)

  

Hypertension, n = No (%)

  

0.632

 

 Yes

104(32.2%)

45(30.0%)

  

 No

219(67.8%)

105(70.0%)

  

PCT, n = No (%)

  

0.338

 

 Yes

49(15.2%)

28(18.7%)

  

 No

274(84.8%)

122(81.3%)

  

ASA grade, n = No (%)

  

0.547

 

 3

38(11.8%)

13(8.7%)

  

 2

98(30.3%)

50(33.3%)

  

 1

187(57.9%)

87(58.0%)

  

Surgical related factors

    

Operation time(min)

  

0.162

 

 Median(IQR)

170(155, 190)

180(155, 210)

  

Intraoperative blood loss (ml)

  

0.836

 

 Median(IQR)

40 (40,50)

40 (40,50)

  

LCA preservation, n = No (%)

 

0.435

 

 Yes

280(86.7%)

126(84.0%)

  

 No

43(13.3%)

24(16.0%)

  

Number of staples fired, n = No (%)

  

0.192

 

 1 or 2

262(81.1%)

129(86.0%)

  

 >2

61(18.9%)

21(14.0%)

  

Surgical approach, n = No (%)

  

0.212

 

 Laparoscopic

270(83.6%)

132(88.0%)

  

 Open

53(16.4%)

18(12.0%)

  

Tumor related factors

    

TD, n = No (%)

  

0.709

 

 ≥ 7 cm

161(49.8%)

72(48.0%)

  

 < 7 cm

162(50.2%)

78(52.0%)

  

Pathological T stage, n = No (%)

  

0.136

 

 Tis, T1, T2,

121(37.5%)

67(44.7%)

  

 T3 and T4

202(62.5%)

83(55.3%)

  

Pathological N stage, n = No (%)

  

0.905

 

 N0

90(27.9%)

41(27.3%)

  

 N1 and N2

233(72.1%)

109(72.7%)

  

TNM stage, n = No (%)

  

0.126

 

 I

35(10.8%)

10(6.7%)

  

 II

129(39.9%)

73(48.7%)

  

 III

159(49.2%)

67(44.7%)

  

Tumor histological differentiation, n = No (%)

 

0.419

 

 High

126(39.0%)

55(36.7%)

  

 Moderate

97(30.0%)

54(36.0%)

  

 Low

100(31.0%)

41(27.3%)

  
  1. AL anastomotic leakage, BMI body mass index, HbA1c glycated hemoglobin, PCT preoperative chemoradiotherapy, ASA American Society of Anesthesiologists physical status classification, IQR interquartile range, LCA left colic artery, TD tumor distance from the anal margin