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Table 2 characteristics of patients in the model group

From: Risk assessment of rectal anastomotic leakage (RAREAL) after DIXON in non-emergency patients with rectal cancer

Factors

AL (n = 26)

NAL (n = 297)

P

 

Patient related factors

 

Age(years, \(\stackrel{-}{x}\pm s\))

61.9 ± 7.6

59.3 ± 11.9

0.276

 

Gender, n = No (%)

  

0.034

 

 Female

4(15.4%)

107(36.0%)

  

 Male

22(84.6%)

190(64.0%)

  

Smoking, n = No (%)

  

0.942

 

 Yes

7(26.9%)

78(26.3%)

  

 No

19(73.1%)

219(73.7%)

  

Alcohol excess, n = No (%)

  

0.364

 

 Yes

8(30.8%)

68(22.9%)

  

 No

18(69.2%)

229(77.1%)

  

Previous history of malignancy, n = No (%)

  

0.530

 

 Yes

2(7.7%)

35(11.8%)

 

 No

24(92.3%)

262(88.2%)

 

BMI(kg/m2, \(\stackrel{-}{x}\pm s\))

22.2 ± 2.1

22.6 ± 2.7

0.473

 

HbA1c, n = No (%)

  

0.032

 

 ≤ 6.3%

22(84.6%)

282(94.9%)

  

 > 6.3%

4(15.4%)

15(5.1%)

  

Diabetes mellitus, n = No (%)

  

0.417

 

 Yes

4(15.4%)

66(22.2%)

  

 No

22(84.6%)

231(77.8%)

  

Hypertension, n = No (%)

  

0.783

 

 Yes

9(34.6%)

95(32.0%)

  

 No

17(65.4%)

202(68.0%)

  

PCT, n = No (%)

  

0.021

 

 Yes

8(30.8%)

41(13.8%)

  

 No

18(69.2%)

256(86.2%)

  

ASA grade, n = No (%)

  

0.916

 

 3

3(11.5%)

35(11.8%)

  

 2

7(26.9%)

91(30.6%)

  

 1

16(61.5%)

171(57.6%)

  

Surgical related factors

    

Operation time(min)

  

0.265

 

 Median(IQR)

180(150.0, 213.4)

170(155.0, 190.0)

  

Intraoperative blood loss (ml)

  

0.572

 

 Median(IQR)

45.0 (27.5,72.5)

40.0 (40.0,50.0)

  

LCA preservation, n = No (%)

 

0.033

 

 Yes

19(73.1%)

261(87.9%)

  

 No

7(26.9%)

36(12.1%)

  

Number of staples fired, n = No (%)

  

0.016

 

 1 or 2

16(61.5%)

246(82.8%)

  

 >2

10(38.5%)

51(17.2%)

  

Surgical approach, n = No (%)

  

0.685

 

 Laparoscopic

21(80.8%)

249(83.8%)

  

 Open

5(19.2%)

48(16.2%)

  

Tumor related factors

    

TD, n = No (%)

  

0.001

 

 ≥ 7 cm

5(19.2%)

156(52.5%)

  

 < 7 cm

21(80.8%)

141(47.5%)

  

Pathological T stage, n = No (%)

  

0.114

 

 Tis, T1, T2,

6(23.1%)

115(38.7%)

  

 T3 and T4

20(76.9%)

182(61.3%)

  

Pathological N stage, n = No (%)

  

0.139

 

 N0

4(15.4%)

86(29.0%)

  

 N1 and N2

22(84.6%)

211(71.0%)

  

TNM stage, n = No (%)

  

0.172

 

 I

3(11.5%)

32(10.8%)

  

 II

6(23.1%)

123(41.4%)

  

 III

17(65.4%)

142(47.8%)

  

Tumor histological differentiation, n = No (%)

 

0.402

 

 High

12(46.2%)

114(38.4%)

  

 Moderate

9(34.6%)

88(29.6%)

  

 Low

5(19.2%)

95(32.0%)

  
  1. AL anastomotic leakage, NAL non anastomotic leakage, BMI body mass index, HbA1c glycated hemoglobin, PCT preoperative chemoradiotherapy, ASA American Society of Anesthesiologists physical status classification, IQR interquartile range, LCA left colic artery, TD tumor distance from the anal margin