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Table 3 characteristics of patients in the validation group

From: Risk assessment of rectal anastomotic leakage (RAREAL) after DIXON in non-emergency patients with rectal cancer

Factors

AL(n = 15)

NAL(n = 135)

P

Patient related factors

Age(years, \(\stackrel{-}{x}\pm s\))

63.3 ± 9.7

58.6 ± 10.8

0.133

Gender, n = No (%)

  

0.130

 Female

3(20.0%)

54(40.0%)

 

 Male

12(80.0%)

81(60.0%)

 

Smoking, n = No (%)

  

0.907

 Yes

5(33.3%)

43(31.9%)

 

 No

10(66.7%)

92(68.1%)

 

Alcohol excess, n = No (%)

  

0.904

 Yes

4(26.7%)

38(28.1%)

 

 No

11(73.3%)

97(71.9%)

 

Previous history of malignancy, n = No (%)

  

0.461

 Yes

1(6.7%)

18(13.3%)

 

 No

14(93.3%)

117(86.7%)

 

BMI(kg/m2, \(\stackrel{-}{x}\pm s\))

22.4 ± 2.2

22.8 ± 2.6

0.473

HbA1c, n = No (%)

  

0.207

 ≤ 6.3%

13(86.7%)

128(94.8%)

 

 > 6.3%

2(13.3%)

7(5.2%)

 

Diabetes mellitus, n = No (%)

  

0.393

 Yes

2(13.3%)

31(23.0%)

 

 No

13(86.7%)

104(77.0%)

 

Hypertension, n = No (%)

  

0.373

 Yes

6(40.0%)

39(28.9%)

 

 No

9(60.0%)

96(71.1%)

 

PCT, n = No (%)

  

0.402

 Yes

4(26.7%)

24(17.8%)

 

 No

11(73.3%)

111(82.2%)

 

ASA grade, n = No (%)

  

0.957

 3

1(6.7%)

12(8.9%)

 

 2

5(33.3%)

45(33.3%)

 

 1

9(57.8%)

78(57.8%)

 

Surgical related factors

Operation time (min)

  

0.478

 Median(IQR)

180(175,210)

180(155,210)

 

Intraoperative blood loss (ml)

  

0.894

 Median(IQR)

40(20,80)

40(40,50)

 

LCA preservation, n = No (%)

  

0.235

 Yes

11(73.3%)

115(85.2%)

 

 No

4(26.7%)

20(14.8%)

 

Number of staples fired, n = No (%)

  

0.136

 1 or 2

11(73.3%)

118(87.4%)

 

 >2

4(26.7%)

17(12.6%)

 

Surgical approach, n = No (%)

  

0.867

 Laparoscopic

13(86.7%)

119(88.1%)

 

 Open

2(13.3%)

16(11.9%)

 

Tumor related factors

TD, n = No (%)

  

0.022

 ≥ 7 cm

3(20.0%)

69(51.1%)

 

 < 7 cm

12(80.0%)

66(48.9%)

 

Pathological T stage, n = No (%)

  

0.352

 Tis, T1, T2,

5(33.3%)

62(45.9%)

 

 T3 and T4

10(66.7%)

73(54.1%)

 

Pathological N stage, n = No (%)

  

0.329

 N0

2(13.3%)

39(28.9%)

 

 N1 and N2

13(86.7%)

96(71.1%)

 

TNM stage, n = No (%)

  

0.925

 I

1(6.7%)

9(6.7%)

 

 II

8(53.3%)

65(48.1%)

 

 III

6(40.0%)

61(45.2%)

 

Tumor histological differentiation, n = No (%)

 

0.288

 High

8(53.3%)

47(34.8%)

 

 Moderate

5(33.3%)

49(36.3%)

 

 Low

2(13.3%)

39(28.9%)

 
  1. AL anastomotic leakage, NAL non anastomotic leakage, BMI body mass index, HbA1c glycated hemoglobin, PCT preoperative chemoradiotherapy, ASA American Society of Anesthesiologists physical status classification, IQR interquartile range, LCA left colic artery, TD tumor distance from the anal margin