Table 2 Subgroup analyses between alcohol consumption and the risk of H. pylori eradication failure
From: Alcohol increases treatment failure for Helicobacter pylori eradication in Asian populations
Variable | Number of Data | Odd ratios (95% CI), % | I2 (%) | P-value for heterogeneity | |
|---|---|---|---|---|---|
Region | Asia | 28 | 1.23 (1.03–1.47) | 41.5 | 0.012 |
Non-Asia | 16 | 0.88 (0.68–1.15) | 45.0 | 0.027 | |
Study design | Prospective study | 30 | 1.13 (0.92–1.38) | 46.2 | 0.003 |
Retrospective study | 14 | 1.05 (0.83–1.32) | 48.8 | 0.021 | |
Treatment regimen | First-line treatment | 41 | 1.09 (0.94–1.26) | 51.4 |  < 0.001 |
Second-line treatment | 3 | 1.25 (0.54–2.93) | 0.00 | 0.952 | |
Proportion of subjects with peptic ulcer | All | 7 | 0.83 (0.65–1.07) | 20.8 | 0.271 |
Portion | 24 | 1.19 (0.93–1.51) | 50.9 | 0.002 | |
Method for assessing HP eradication | Urea breath test | 23 | 0.98 (0.82–1.16) | 39.7 | 0.027 |
Others | 7 | 0.75 (0.51–1.09) | 16.0 | 0.308 | |