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Table 3 Subgroup analyses between alcohol consumption and the risk of H. pylori eradication failure in Asia

From: Alcohol increases treatment failure for Helicobacter pylori eradication in Asian populations

Variable

Number of Data

Odd ratios (95% CI), %

I2 (%)

P-value for heterogeneity

Duration of therapy

7 days

19

1.23 (0.94–1.60)

47.4

0.012

 > 7 days

8

1.17 (1.01–1.25)

40.4

0.109

Antibiotic types

Clarithromycin

20

1.15 (0.91–1.45)

41.9

0.026

Non-Clarithromycin

8

1.18 (1.10–1.26)

44.5

0.082

Nitroimidazoles

3

1.16 (1.09–1.24)

0.00

0.461

Non- Nitroimidazoles

25

1.24 (0.99–1.57)

46.2

0.007

Treatment options

VPZ-based therapy

5

1.73 (0.98–3.05)

0.00

0.897

bismuth-containing quadruple therapy

7

1.17 (1.10–1.25)

40.7

0.028

Alcohol consumption

 < 40 g/day

4

1.15 (0.54–2.45)

59.1

0.062

 > 40 g/day

3

3.17 (1.56–6.41)

0.00

0.520

  1. Abbreviations: HP Helicobacter pylori, VPZ Vonoprazan