Table 5 Route of delivery: C- section vs. Vaginal

Median age at delivery (years)

31 (27–32)

28 (25–32)

0.021

BMI > 30

40 (26%)

33 (19%)

0.157

Median age at IBD diagnosis (years)

22 (16–26)

22 (17–26)

0.436

Smoking

37 (24%)

40 (24%)

0.914

More than 5 years between diagnosis and delivery

117 (76%)

116 (68%)

0.117

Previous surgery for IBD

77 (50%)

48 (28%)

< 0.001

Ileocolonic involvement

67 (54%)

66 (50%)

0.564

Perianal disease before delivery

43 (79%)

1 (8%)

< 0.001

First delivery?

86 (56%)

104 (62%)

0.335

Status of perianal disease

< 0.001

None

Healed

Quiescent

Active

103 (67%)

16 (10%)

20 (13%)

14 (9%)

158 (93%)

10 (6%)

0

1 (1%)

Steroids

Before delivery

During delivery

After delivery

Any time

54 (35%)

19 (12%)

34 (22%)

64 (42%)

56 (33%)

15 (9%)

18 (11%)

69 (41%)

0.683

0.302

0.004

0.855

Biologics

Before delivery

During delivery

After delivery

Any time

70 (46%)

43 (28%)

66 (43%)

80 (52%)

63 (37%)

43 (25%)

74 (44%)

86 (51%)

0.123

0.590

0.907

0.802

Immunomodulators

Before delivery

During delivery

After delivery

Any time

37 (24%)

10 (6%)

20 (13%)

42 (27%)

28 (17%)

2 (2%)

13 (8%)

37 (22%)

0.089

0.011

0.111

0.247

5-ASA

Before delivery

During delivery

After delivery

Any time

39 (25%)

21 (14%)

31 (20%)

51 (33%)

68 (40%)

31 (18%)

50 (30%)

82 (48%)

0.005

0.261

0.054

0.006

Antibiotics

Before delivery

During delivery

Any time

3 (2%)

6 (4%)

9 (6%)

2 (1%)

1 (1%)

3 (2%)

0.573

0.041

0.052

Post-delivery perianal flare

17 (11%)

4 (2%)

0.002

Median interval between delivery and flare (months)

2 (0–13)

4.5 (2–10)

0.731