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Table 3 Effect of early antibiotic treatment strategies on prognosis of AP

From: Effect of early antibiotic treatment strategy on prognosis of acute pancreatitis

   

Antibiotics

None

P value

Biliary Pancreatitis

     

SAP

 

n = 105

n = 11

 

Laparotomy, n(%)

22(20.9)

8(72.7)

< 0.001*

Length of hospital stay, days

50.3 ± 33.6

91.0 ± 49.4

0.024*

In-hospital mortality,n(%)

12(11.4)

2(18.2)

0.621

AKI, n(%)

47(44.7)

6(54.5)

0.546

CRRT,n(%)

10(9.5)

3(27.3)

0.107

MV,n(%)

52(49.5)

10(90.9)

0.010*

MSAP

 

n = 212

n = 51

 

Length of hospital stay, days

18.2 ± 10.9

91.0 ± 49.4

0.001*

In-hospital mortality,n(%)

0(0)

2(3.9)

0.037*

AKI, n(%)

13(6.1)

3(5.5)

0.947

MAP

 

n = 69

n = 204

 

Length of hospital stay, days

9.07 ± 3.8

12.25 ± 5.0

0.060

Hyperlipidemic pancreatitis

    

SAP

 

n = 85

n = 5

 

Laparotomy, n(%)

7(8.2)

1(20)

0.369

Length of hospital stay, days

44.4 ± 24.0

54.0 ± 39.1

0.075

In-hospital mortality,n(%)

6(7.1)

0

1

AKI, n(%)

35(41.2)

0

0.152

CRRT,n(%)

15(17.6)

0

0.588

MV,n(%)

40(47.1)

3(60.0)

0.667

MSAP

 

n = 78

n = 46

 

Length of hospital stay, days

30.2 ± 14.7

21.3 ± 9.9

0.064

In-hospital mortality,n(%)

1(1.2)

0

1

AKI, n(%)

4(5.1)

3(6.5)

0.710

MAP

 

n = 48

n = 90

 

Length of hospital stay, days

17.9 ± 9.9

16.9 ± 8.3

0.921

Alcoholic Pancreatitis

    

SAP

 

n = 13

n = 2

 

Laparotomy, n(%)

2(15.3)

0(0)

1

Length of hospital stay, days

54.4 ± 56.1

52.5 ± 26.1

0.516

In-hospital mortality,n(%)

3(23.1)

0(0)

1

AKI, n(%)

3(23.1)

2(100)

0.095

CRRT,n(%)

2(15.3)

0(0)

1

MV,n(%)

10(66.7)

1(50)

0.476

MSAP

 

n = 15

n = 10

 

Length of hospital stay, days

27.4 ± 12.4

21.6 ± 9.1

0.233

In-hospital mortality,n(%)

1(6.6)

0

1

AKI, n(%)

1(6.6)

0

1

MAP

 

n = 9

n = 22

 

Length of hospital stay, days

19.0 ± 9.4

9.8 ± 4.1

0.034*

Other

    

SAP

 

n = 22

n = 1

 

Laparotomy, n(%)

2 (15.3)

0(0)

1

Length of hospital stay, days

54.4 ± 56.1

–

0.516

In-hospital mortality,n(%)

3 (23.1)

0(0)

1

AKI, n(%)

3(23.1)

2(100)

0.095

CRRT,n(%)

2(15.3)

0(0.0)

1

MV,n(%)

10(66.7)

1(50)

0.476

MSAP

 

n = 17

n = 0

 

Length of hospital stay,days

27.4 ± 12.4

21.6 ± 9.1

0.233

In-hospital mortality,n(%)

1(6.6)

0

1

AKI, n(%)

1(6.6)

0

1

MAP

 

n = 6

n = 10

 

Length of hospital stay,days

15.8 ± 7.8

12.0 ± 5.3

0.317

  1. *P < 0.05