Table 4 Logistic regression analysis for adverse drug reactions

Male

0.556 (0.143–2.162)

0.397

Age (ref. ≥ 70 years)

0.178

19 ~ 29 years

0.143 (0.004–4.612)

30 ~ 39 years

1.333 (0.057–31.121)

40 ~ 49 years

0.083 (0.003–2.603)

50 ~ 59 years

0.571 (0.028–11.849)

60 ~ 69 years

0.125 (0.004–3.996)

Smoking history

1.336 (0.334–5.343)

0.881

Oral ulcer

1.454 (0.373–5.679)

0.590

Genital ulcer

1.701 (0.271–10.686)

0.571

Ocular lesion

2.200 (0.440-11.006)

0.337

Skin lesion

4.429 (1.095–17.915)

0.037

3.205 (0.576–17.827)

0.183

Arthralgia

3.810 (0.901–16.100)

0.069

5.581 (0.894–34.855)

0.066

Previous treatment for BD

0.081 (0.008–0.874)

0.038

0.062 (0.002–1.682)

0.099

Previous medical history

0.722 (0.165–3.157)

0.666

Concomitant diseases

0.714 (0.176–2.898)

0.638

Concomitant medications

0.278 (0.035–2.227)

0.228

Disease duration (a month)

0.973 (0.949–0.997)

0.026

0.976 (0.953–0.999)

0.042

Total amount of adalimumab (mg)

0.999 (0.997–1.001)

0.251

Frequency of adalimumab administration (times)

0.963 (0.900–1.030)

0.272