Table 2 Layout of the anthropometric and clinical data collected at inclusion and at each visit^a

Basic data

 • Date of birth

 • Gender

 • Anthropometrics

  ◦ Height

  ◦ Weight

  ◦ Waist circumference

  ◦ Hip circumference

  ◦ Blood pressure

Previous and present cirrhosis history and severity

 • Date and modality of cirrhosis diagnosis

 • Underlying etiology

 • Decompensating event (type and date)

Assessment of hepatic encephalopathy

 • Animal naming test

Medical History

 • Previous and present relevant comorbidities and date of diagnosis, including:

  ◦ Hypertension, dyslipidemia

  ◦ Cardiovascular diseases, including PCI and CABG

  ◦ Congestive heart failure

  ◦ Atrial fibrillation/flutter

  ◦ Stroke

  ◦ Malignancies

 • Current or recent medication (including over-the-counter, traditional/herbal remedies, and nutritional supplements)

Family History

 • Family medical history

Lifestyle

 • Smoking – Yes/No/Ex, and frequency of smoking (pack-years)

 • Coffee consumption – cups/days

 • Alcohol consumption

 • Physical activity and fitness

 • Patient reported quality of life

 • Sleep quality assessment

Hand grip strength

FibroScan

 • VCTE

 • CAP

MR-examination (20 min)

 • Body composition: VAT, ASAT, liver PDFF, thigh FFMV and MFI, spinal erector FFMV and MFI, liver volume, and spleen volume.

 • Muscle Assessment Score (MAsS): MVZ and sex-adjusted MFI

 • L3-SMI

 • Liver MRE

 • HCC screening

Muscle function and physical frailty

 • Short physical performance battery (SPPB)

 • Hand grip strength (HGS)

 • Liver frailty index (LFI)