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Table 3 The association between four IR indicators and both hepatic steatosis, hepatic fibrosis

From: Association of insulin resistance indicators with hepatic steatosis and fibrosis in patients with metabolic syndrome

Indicators

Hepatic steatosis

Hepatic fibrosis

Crude Model

Adjusted Modela

Crude Model

Adjusted Modelb

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

HOMA-IR

        

 < 3.11

Ref

Ref

Ref

Ref

 3.11–5.81

2.41 (1.17–4.94)

0.020

2.36 (1.14–4.87)

0.023

3.29 (1.16–9.37)

0.028

2.84 (0.95–8.50)

0.060

 ≥ 5.81

5.30 (2.65–10.62)

< 0.001

4.54 (2.06–10.03)

0.001

7.25 (3.34–15.76)

< 0.001

4.47 (1.87–10.66)

0.002

TyG

      

 < 8.90

Ref

Ref

Ref

Ref

 8.90–9.30

1.12 (0.58–2.15)

0.726

1.11 (0.61–2.02)

0.708

0.87 (0.37–2.01)

0.724

0.72 (0.33–1.57)

0.383

 ≥ 9.30

2.28 (1.10–4.74)

0.030

2.24 (1.15–4.39)

0.021

1.41 (0.58–3.41)

0.420

0.79 (0.30–2.09)

0.610

TyG-WHtR

      

 < 5.55

Ref

Ref

Ref

Ref

 5.55–6.29

2.77 (1.48–5.19)

0.003

2.23 (1.17–4.24)

0.018

2.34 (1.05–5.20)

0.039

1.53 (0.49–4.73)

0.439

 ≥ 6.29

7.01 (4.24–11.57)

< 0.001

6.07 (3.74–9.83)

< 0.001

11.42 (5.89–22.15)

< 0.001

9.21 (2.90–29.22)

< 0.001

METS-IR

      

 < 46.27

Ref

Ref

Ref

Ref

 46.27–57.04

1.49 (0.85–2.60)

0.148

1.53 (0.78–2.99)

0.200

1.05 (0.46–2.43)

0.900

1.28 (0.67–2.48)

0.428

 ≥ 57.04

6.27 (4.00–9.81)

< 0.001

5.60 (3.34–9.40)

< 0.001

4.61 (2.25–9.44)

< 0.001

5.04 (2.47–10.27)

< 0.001

  1. METS-IR metabolic score for insulin resistance, TyG triglyceride/glucose, HOMA-IR homeostasis model assessment of IR, TyG-WHtR triglyceride glucose-waist-to-height ratio, OR odds ratio, CI confidence interval
  2. Crude model: confounding variables were not adjusted
  3. aAdjusted Model: education level, hepatitis, cardiovascular disease (CVD), alanine aminotransferase (ALT), drug for hypertension, and protein were adjusted
  4. b Adjusted Model: family income-to-poverty ratio, diastolic blood pressure, CVD, ALT, aspartate aminotransferase, gamma glutamyl transferase, platelet count, albumin, drug for diabetes, antiviral agents, and hepatic steatosis were adjusted