Table 2 Characteristics of esophageal cancer patients diagnosed at AUBMC between 1995 and 2019 by histological type
Factor | Variable | ESCC (n = 54) | EAC (n = 56) | p value |
|---|---|---|---|---|
Age n = 110 | < 50 | 16.7% | 12.5% | 0.786 |
50–69 | 51.9% | 57.1% | ||
≥70 | 31.5% | 30.4% | ||
Sex n = 110 | Male | 53.7% | 87.5% | < 0.001 |
Female | 46.3% | 12.5% | ||
BMI n = 84 | Underweight | 21.4% | 2.4% | .005 |
Normal range | 45.2% | 28.6% | ||
Overweight | 21.4% | 50% | ||
Obese | 11.9% | 14.3% | ||
Tobacco consumption n = 93 | Current or past smoker | 67.4% | 44% | .024 |
Alcohol consumption n = 88 | Yes | 29.3% | 21.3% | .388 |
Pre-existing esophageal disease n = 64 | GERD | 20.7% | 28.6% | 0.469 |
Barrett’s | 4.2% | 21.4% | 0.107 | |
Esophageal injury | 6.9% | 0% | 0.153 | |
Pre-existing gastric disease n = 64 | Atrophic gastritis | 30.8% | 10.5% | 0.055 |
H. pylori infection | 11.5% | 10.5% | 1.000 | |
Hiatal hernia | 11.5% | 10.5% | 1.000 | |
Tumor location n = 101 | Upper esophagus | 39.6% | 1.9% | <.001 |
Middle esophagus | 31.3% | 9.4% | ||
Lower esophagus | 25% | 32.1% | ||
GE junction | 4.2% | 56.6% | ||
Tumor location combined n = 101 | Upper + Middle | 70.8% | 11.3% | <.001 |
Lower + GE junction | 29.2% | 88.7% | ||
Tumor stage n = 54 | I | 7.7% | 11.1% | .490 |
II | 20.5% | 8.9% | ||
III | 54.6% | 62.2% | ||
IV | 15.4% | 17.8% | ||
Tumor grade n = 93 | Poorly differentiated | 19.1% | 32.6% | .385 |
Moderately differentiated | 70.2% | 60.9% | ||
Well differentiated | 8.5% | 6.5% |