Table 1 Baseline characteristics of patients in the study cohort at FPGC diagnosis
Characteristics | All patients | Development of RGC | ||
|---|---|---|---|---|
| Â | Â | No | Yes | p |
Patients, n | 17,782 | 17,555 | 227 | Â |
Year of diagnosis, median (IQR) | 2007 (2003–2011) | 2007 (2003–2011) | 2007 (2004–2011) | 0.799 |
Year group, n (%) | Â | Â | Â | 0.264 |
 2000–2004 | 6070 (34.1) | 6000 (34.2) | 70 (30.8) |  |
 2005–2009 | 5702 (32.1) | 5618 (32.0) | 84 (37.0) |  |
 2010–2015 | 6010 (33.8) | 5937 (33.8) | 73 (32.2) |  |
Age at diagnosis (years), median (IQR) | 69 (59–77) | 69 (59–77) | 66 (55–74) | < 0.001 |
Age group, n (%) | Â | Â | Â | 0.024 |
 < 45 years | 993 (5.6) | 974 (5.5) | 19 (8.4) |  |
 45–54 years | 2110 (11.9) | 2075 (11.8) | 35 (15.4) |  |
 55–64 years | 3642 (20.5) | 3594 (20.5) | 48 (21.1) |  |
 65–74 years | 5183 (29.1) | 5113 (29.1) | 70 (30.8) |  |
 75 + years | 5854 (32.9) | 5799 (33.0) | 55 (24.2) |  |
Sex, n (%) | Â | Â | Â | 0.410 |
 Male | 10,848 (61.0) | 10,703 (61.0) | 145 (63.9) |  |
 Female | 6934 (39.0) | 6852 (39.0) | 82 (36.1) |  |
Race, n (%) | Â | Â | Â | 0.446 |
 NH White | 8197 (46.1) | 8102 (46.2) | 95 (41.9) |  |
 NH Black | 2291 (12.9) | 2264 (12.9) | 27 (11.9) |  |
 NH Asian | 3905 (22.0) | 3844 (21.9) | 61 (26.9) |  |
 Hispanic | 3265 (18.4) | 3223 (18.4) | 42 (18.5) |  |
 NH Others | 124 (0.7) | 122 (0.7) | 2 (0.9) |  |
Marital status, n (%) | Â | Â | Â | 0.028 |
 Married | 10,779 (60.6) | 10,620 (60.5) | 159 (70.0) |  |
 Widowed | 2811 (15.8) | 2784 (15.9) | 27 (11.9) |  |
 Single | 2103 (11.8) | 2077 (11.8) | 26 (11.5) |  |
 Divorced | 1313 (7.4) | 1303 (7.4) | 10 (4.4) |  |
 Other/Unknown | 776 (4.4) | 771 (4.4) | 5 (2.2) |  |
Area, n (%) | Â | Â | Â | 1.000 |
 Urban | 16,253 (91.4) | 16,046 (91.4) | 207 (91.2) |  |
 Rural | 1529 (8.6) | 1509 (8.6) | 20 (8.8) |  |
Income, n (%) | Â | Â | Â | 0.233 |
 <$55,000 | 2022 (11.4) | 2004 (11.4) | 18 (7.9) |  |
 $55,000–64,999 | 2657 (14.9) | 2624 (14.9) | 33 (14.5) |  |
 $65,000–74,999 | 5619 (31.6) | 5536 (31.5) | 83 (36.6) |  |
 $75,000+ | 7484 (42.1) | 7391 (42.1) | 93 (41.0) |  |
Tumor site, n (%) | Â | Â | Â | 0.319 |
 Cardia | 3763 (21.2) | 3720 (21.2) | 43 (18.9) |  |
 Middle | 4910 (27.6) | 4835 (27.5) | 75 (33.0) |  |
 Distal | 6837 (38.4) | 6754 (38.5) | 83 (36.6) |  |
 NOS | 2272 (12.8) | 2246 (12.8) | 26 (11.5) |  |
Tumor stage, n (%) | Â | Â | Â | 0.064 |
 Localized | 7427 (41.8) | 7318 (41.7) | 109 (48.0) |  |
 Regional | 10,355 (58.2) | 10,237 (58.3) | 118 (52.0) |  |
T Category, n (%) | Â | Â | Â | 0.385 |
 T1 | 4878 (27.4) | 4817 (27.4) | 61 (26.9) |  |
 T2 | 2507 (14.1) | 2466 (14.0) | 41 (18.1) |  |
 T3 | 6391 (35.9) | 6314 (36.0) | 77 (33.9) |  |
 T4 | 4006 (22.5) | 3958 (22.5) | 48 (21.1) |  |
N Category, n (%) | Â | Â | Â | 0.016 |
 N0 | 8338 (46.9) | 8213 (46.8) | 125 (55.1) |  |
 N+ | 9444 (53.1) | 9342 (53.2) | 102 (44.9) |  |
Size, n (%) | Â | Â | Â | 0.442 |
 < 5 cm | 9688 (54.5) | 9555 (54.4) | 133 (58.6) |  |
 5 + cm | 5926 (33.3) | 5856 (33.4) | 70 (30.8) |  |
 Unknown | 2168 (12.2) | 2144 (12.2) | 24 (10.6) |  |
Grade, n (%) | Â | Â | Â | 0.787 |
 G1 | 1059 (6.0) | 1046 (6.0) | 13 (5.7) |  |
 G2 | 4975 (28.0) | 4916 (28.0) | 59 (26.0) |  |
 G3 | 10,866 (61.1) | 10,725 (61.1) | 141 (62.1) |  |
 Unknown | 882 (5.0) | 868 (4.9) | 14 (6.2) |  |
Lauren classification, n (%) | Â | Â | Â | 0.791 |
 Intestinal | 12,216 (68.7) | 12,057 (68.7) | 159 (70.0) |  |
 Diffuse | 4246 (23.9) | 4196 (23.9) | 50 (22.0) |  |
 Mixed/Others | 1320 (7.4) | 1302 (7.4) | 18 (7.9) |  |
Surgical mode, n (%) | Â | Â | Â | 0.025 |
 DG | 6027 (33.9) | 5946 (33.9) | 81 (35.7) |  |
 PG | 1221 (6.9) | 1196 (6.8) | 25 (11.0) |  |
 Others | 10,534 (59.2) | 10,413 (59.3) | 121 (53.3) |  |