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Table 1 Basic characteristics of patients

From: Safety and efficacy of a low-dose combination of midazolam, alfentanil, and propofol for deep sedation of elderly patients undergoing ERCP

Parameter

Age 50–64

n = 202

Age 65–79

n = 216

Age ≥ 80

n = 192

P-Value

 

Age (y)

60.7 ± 2.7

73.5 ± 4.4

86.9 + 4.1

P < 0.001

 

Gender

     

 Male

107 (53.0)

121 (56.0)

114 (59.4)

0.441

 

 Female

95 (47.0)

95 (44.0)

78 (40.6)

 

Weight (kg)

62.9 ± 8.1

62.3 ± 5.0

61.5 ± 6.1

0.106

 

BMI (kg/m2)

22.7 ± 2.7

22.6 ± 2.2

22.4 ± 2.5

0.408

 

ASA

     

 I

113 (55.9)

24 (11.1)

0 (0.0)

P < 0.001

 

 II

71 (35.1)

160 (74.1)

114 (59.4)

 

 III

18 (8.9)

32 (14.8)

78 (40.6)

 

Comorbidity

     

 Hypertension

42 (20.8)

77 (35.6)

95 (49.5)

P < 0.001

 

 Diabetes

17 (8.4)

30 (13.9)

43 (22.4)

P < 0.001

 

 Myocardial infarction

10 (5.0)

20 (9.3)

25 (13.0)

0.020

 

 Cerebral infarction

1 (0.5)

11 (5.1)

19 (9.9)

P < 0.001

 

 Renal disease

5 (2.5)

8 (3.7)

15 (7.8)

0.030

 

 Liver disease

4 (2.0)

9 (4.2)

12 (6.3)

0.102

 

 all

68 (33.7)

142 (65.7)

148 (77.1)

P < 0.001

 

Baseline SBP

132.2 ± 13.6

133.0 ± 17.5

137.2 ± 17.9

0.005

 

Baseline DBP

75.0 ± 6.8

75.9 ± 7.6

79.0 ± 7.2

P < 0.001

 

Baseline HR

75.2 ± 7.1

73.1 ± 7.2

76.3 ± 5.4

P < 0.001

 

Baseline SpO2

97.6 ± 1.1

97.7 ± 1.0

97.2 ± 1.2

P < 0.001

 

Baseline BIS

92.9 ± 1.8

93.2 ± 1.7

92.6 ± 1.8

0.004

 
  1. Data are presented as mean ± standard deviation or number (percentage)
  2. BMI Body mass index, ASA American society of anesthesiologists, SBP Systolic blood Pressure, DBP Diastolic blood pressure, HR Heart rate, SpO2 Saturation of Peripheral Oxygen, BIS Bispectral Index