Skip to main content

Table 2 Comparison of clinicopathological factors between non-older and older patients

From: Impact of severe postoperative complications on the prognosis of older patients with colorectal cancer: a two-center retrospective study

 

n = 760

Non-older group

n = 569

Older group

n = 191

P-value d

Age, years

  

67.9

± 8.49

83.8

± 3.40

< 0.001

Sex

Female

Male

331

429

234

335

(41%)

(59%)

97

94

(51%)

(49%)

0.019

BMI, kg/m2

> 22

≤ 22

389

371

302

267

(53%)

(47%)

87

104

(46%)

(54%)

0.071

ASA-PS

≥ 3

< 3

153

607

92

477

(16%)

(84%)

61

130

(32%)

(68%)

< 0.001

Preoperative albumin level, g/dl

≤ 3.5

> 3.5

159

601

103

466

(18%)

(82%)

56

135

(29%)

(71%)

0.001

Location

Right

Left

Rectum

273

236

251

186

187

196

(33%)

(33%)

(34%)

87

49

55

(45%)

(26%)

(29%)

0.005

Preoperative treatment

(chemo-radio or chemo therapy)

Presence

Absence

11

749

9

560

(2%)

(98%)

2

189

(1%)

(99%)

0.592

Treatment for colorectal obstruction

Presence

Absence

48

712

33

536

(6%)

(94%)

15

176

(8%)

(92%)

0.312

Histopathological typea

por/sig/muc

tub/pap

62

698

40

529

(7%)

(93%)

22

169

(12%)

(88%)

0.049

T stageb

T4

T1-3

138

622

107

462

(19%)

(81%)

31

160

(16%)

(84%)

0.424

N stageb

N1-2

N0

284

476

215

354

(38%)

(62%)

69

122

(36%)

(64%)

0.681

pStageb

II, III

I

557

203

404

165

(71%)

(29%)

153

38

(80%)

(20%)

0.013

Lymphatic invasion

Presence

Absence

483

277

348

221

(61%)

(39%)

135

56

(71%)

(29%)

0.018

Venous invasion

Presence

Absence

420

340

309

260

(54%)

(46%)

111

80

(58%)

(42%)

0.359

Surgical procedure

Ileocecal resection

Right hemicolectomy

Transverse colectomy

Left hemicolectomy

Sigmoidectomy

Hartmann operation

Rectal resection

93

128

46

43

184

24

240

60

87

33

32

146

14

195

(11%)

(15%)

(6%)

(6%)

(26%)

(2%)

(34%)

33

41

13

11

38

10

45

(17%)

(21%)

(7%)

(6%)

(20%)

(5%)

(24%)

0.005

Stoma

Permanent stoma

Diverting stoma

Absence

69

22

669

48

18

503

(9%)

(3%)

(88%)

21

4

166

(11%)

(2%)

(87%)

0.442

Elective or urgent surgery

Elective

Urgent

747

13

560

9

(98%)

(2%)

187

4

(98%)

(2%)

0.636

Surgical approach

Open

Laparoscopic

226

534

154

415

(27%)

(73%)

72

119

(38%)

(62%)

0.005

Operative blood loss, ml

≥ 100

< 100

236

524

168

401

(30%)

(70%)

68

123

(36%)

(64%)

0.116

Operative time, min

≥ 250

< 250

377

383

298

271

(52%)

(48%)

79

112

(41%)

(59%)

0.008

Severe postoperative complicationc

Presence

Absence

56

704

42

527

(8%)

(92%)

14

177

(7%)

(93%)

0.981

Postoperative hospital stay, days

  

16.2

± 12.2

18.6

± 18.3

0.041

Adjuvant chemotherapy

Presence

Absence

230

530

207

362

(36%)

(64%)

23

168

(12%)

(88%)

< 0.001

  1. a: According to the Japanese classification of colorectal carcinoma, 8th edition
  2. b: According to the 7th edition of the UICC/TNM staging system
  3. c: Grade 3 or higher according to the Clavien–Dindo classification
  4. d: P values are from the chi-square test or Student’s t-test
  5. tub tubular adenocarcinoma, pap papillary adenocarcinoma, por poorly differentiated adenocarcinoma, sig signet-ring cell carcinoma, muc mucinous adenocarcinoma, ASA-PS American Society of Anesthesiologists Physical Status, BMI body mass index