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Table 2 Multiple non-inferiority analysis for Hp eradication rates

From: Comparison of vonoprazan dual therapy, quadruple therapy and standard quadruple therapy for Helicobacter pylori infection in Hainan: a single-center, open-label, non-inferiority, randomized controlled trial

 

Group

Eradication rate And 95% CI (ITT)

Eradication rate And 95% CI (PP)

Difference [95% CI] (ITT)

Difference [95% CI] (PP)

P †

V1 and V2

V1

84.4%

73.4–95.5%

88.4%

78.4–98.4%

−14.9-14.9%

−8.2-16.8%

0.095(ITT) 0.186(PP)

V2

84.4%

73.4–95.5%

92.7%

84.4–101.0%

V3 AndV2

V3

84.4%

73.4–95.5%

88.4%

78.4–98.4%

−14.9-14.9%

−8.2-16.8%

0.095(ITT) 0.186 (PP)

V2

84.4%

73.4–95.5%

92.7%

84.4–101.0%

  1. P † p-value for non-inferiority test
  2. CI confidence interval, ITT intention-to-treat, PP per-protocol