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  1. The methylation SEPT9 (mSEPT9) appeared to be effective for hepatocellular carcinoma (HCC) detection. However, its performance in high-risk population has not been validated. We designed a pilot study and aime...

    Authors: Kepu Zheng, Leiyang Dai, Yingpeng Zhao, Laibang Li, Wang Li, Xibing Zhang, Qiuming Su, Ruichao Wu, Yizhou Jiang, Yonglin Chen and Jianghua Ran
    Citation: BMC Gastroenterology 2023 23:260
  2. N6A methylation (m6A) is a significant epigenetic modification that critically impacts post-transcriptional regulation and tumor occurrence and development. While previous studies have identified a role for ep...

    Authors: Zhen Zhang, Wenhui Gao, Zhuo Liu, Shuxian Yu, Huiying Jian, Zongwei Hou and Puhua Zeng
    Citation: BMC Gastroenterology 2023 23:259
  3. Crohn’s diseases and ulcerative colitis, both of which are chronic immune-mediated disorders of the gastrointestinal tract are major contributors to the overarching Inflammatory bowel diseases. It has become i...

    Authors: Raed M. Alsulaiman, Abdulaziz A. Al-Quorain, Fahad A. Al-Muhanna, Stanley Piotrowski, Ezzeddin A. Kurdi, Chittibabu Vatte, Ahmed A. Alquorain, Noorah H. Alfaraj, Abdulaziz M. Alrezuk, Fred Robinson, Alexa K. Dowdell, Turki A. Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla…
    Citation: BMC Gastroenterology 2023 23:258
  4. Authors: Julia Hanevelt, Jelle F. Huisman, Laura W. Leicher, Miangela M. Lacle, Milan C. Richir, Paul Didden, Joost M. J. Geesing, Niels Smakman, Jochim S. Terhaar Sive Droste, Frank ter Borg, A. Koen Talsma, Ruud W. M. Schrauwen, Bob J. van Wely, Ingrid Schot, Maarten Vermaas, Philip Bos…
    Citation: BMC Gastroenterology 2023 23:256

    The original article was published in BMC Gastroenterology 2023 23:214

  5. Patients with inflammatory bowel disease report multiple symptoms, but the relationships among co-occurring symptoms are poorly understood. This study aimed to examine the prevalence of symptoms and explore sy...

    Authors: Ingunn Johansen, Milada Cvancarova Småstuen, Stine Torp Løkkeberg, Vendel Ailin Kristensen, Marte Lie Høivik, Charlotte Lund, Bjørn Olsen, Vibeke Strande, Gert Huppertz-Hauss, Tone Bergene Aabrekk, May-Bente Bengtson, Petr Ricanek, Trond Espen Detlie, Svein Oskar Frigstad, Lars-Petter Jelsness-Jørgensen and Randi Opheim
    Citation: BMC Gastroenterology 2023 23:255
  6. Gallstone disease poses a significant health burden in the United States. Choledocholithiasis and cholangitis are common complications of gallstone disease for which data on current epidemiological trends are ...

    Authors: Suqing Li, Leonardo Guizzetti, Christopher Ma, Abdel Aziz Shaheen, Elijah Dixon, Chad Ball, Sachin Wani and Nauzer Forbes
    Citation: BMC Gastroenterology 2023 23:254
  7. Periampullary diverticulum (PAD) may make the performance of endoscopic retrograde cholangiopancreatography (ERCP) in patients with choledocholithiasis more difficult and may increase complication rates. The p...

    Authors: He-xian Shi, Yong-qiang Ye, Hai-wang Zhao, De-cai Kong, Shan-zhou Huang, Qian Yan, Yu-bin Chen, Ping Zhang, Sheng Chen, Bao-hua Hou and Chuan-zhao Zhang
    Citation: BMC Gastroenterology 2023 23:252
  8. Colonic self-expandable metallic stent (SEMS) placement enables preoperative total colonoscopy (TCS) in patients with obstructive colorectal cancer. Following SEMS placement, it is possible to assess the prese...

    Authors: Shuichi Itonaga, Shohei Hamada, Eikichi Ihara, Hitoshi Honma, Hiroki Fukuya, Akito Ookubo, Taisuke Sasaki, Daisuke Yoshimura, Makoto Nakamuta, Yorinobu Sumida and Naohiko Harada
    Citation: BMC Gastroenterology 2023 23:251
  9. Platelet (PLT) transfusion was the most practical way to increase patients’ PLT counts before invasive hepatic procedures such as radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). A novel drug ...

    Authors: Hideo Yoshida, Takamasa Ohki, Mineo Kanezaki, Takuma Teratani, Shinpei Sato, Shuntaro Obi, Takahisa Sato, Masatoshi Akamatsu, Koji Uchino and Hiroyoshi Taniguchi
    Citation: BMC Gastroenterology 2023 23:250
  10. This study aimed to evaluate the efficacy, adverse events, patient compliance, and cost of dual therapy with Ilaprazole-amoxicillin (IA) at high dose versus Ilaprazole-amoxicillin-furazolidone-bismuth (IAFB) q...

    Authors: Xiao-Dong Zhang, Da-Ya Zhang, Run-Xiang Chen, Shi-Ju Chen, Chen Chen, Fan Zeng, Shi-Mei Huang, Da Li and Fei-Hu Bai
    Citation: BMC Gastroenterology 2023 23:249
  11. Gastrointestinal Tuberculosis (GITB) and Crohn’s disease (CD) are both chronic granulomatous diseases with a predilection to involve primarily the terminal ileum. GITB is often considered a disease of the deve...

    Authors: Arup Choudhury, Jasdeep Dhillon, Aravind Sekar, Pankaj Gupta, Harjeet Singh and Vishal Sharma
    Citation: BMC Gastroenterology 2023 23:246
  12. Some patients with Crohn’s disease report posttraumatic growth, which can promote reductions in anxiety and depression, and improve the patient’s quality of life. However, the process of posttraumatic growth r...

    Authors: Ying Wang, Chen Zhang and Yunxian Zhou
    Citation: BMC Gastroenterology 2023 23:244
  13. Gastric anisakiasis typically causes severe abdominal symptoms; however, we incidentally detected asymptomatic gastric anisakiasis cases during esophagogastroduodenoscopy. The factors associated with developin...

    Authors: Yutaka Okagawa, Tetsuya Sumiyoshi, Takayuki Imagawa, Hiroya Sakano, Fumito Tamura, Yohei Arihara, Yusuke Kanari, Akira Sakurada, Shutaro Oiwa, Takashi Jin, Yusuke Tomita, Shinya Minami, Hiroyuki Hisai, Hirohito Muramatsu, Shinichi Katsuki, Masahiro Maeda…
    Citation: BMC Gastroenterology 2023 23:243
  14. Vertical transmission of hepatitis C virus (HCV) is the primary cause of hepatitis C in the pediatric population. Nonetheless, only a small proportion of HCV-exposed children are tested. This study aimed to me...

    Authors: Ndeye Licka Dieye, Mine Varol, Shauna C. Zorich, Amy E. Millen, Karl O. A. Yu and Oscar G. Gómez-Duarte
    Citation: BMC Gastroenterology 2023 23:242
  15. Thiopurines continue to play an important role in the treatment of inflammatory bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. Especially, hematopoietic toxicity ma...

    Authors: Shizuka Suzuki, Kan Uchiyama, Yutaro Motoi, Yuuki Yoshii, Yukari Inoue, Takahiro Kubota, Shunichi Odahara, Yuichiro Ohtaki, Shinichiro Takami, Zensho Ito, Nobuhiro Sato, Toshifumi Ohkusa, Shigeo Koido and Masayuki Saruta
    Citation: BMC Gastroenterology 2023 23:239
  16. Gastric neuroendocrine carcinoma (GNEC) is a rare histology of gastric cancer. The retrospective study was designed to construct and validate a nomogram for predicting the cancer-specific survival (CSS) of pos...

    Authors: Xue Song, Yangyang Xie and Yafang Lou
    Citation: BMC Gastroenterology 2023 23:238
  17. Parental liver transplantation (PLT) improves long-term survival rates in paediatric hepatic failure patients; however, the mechanism of PLT-induced postoperative pulmonary complications (PPCs) is unclear.

    Authors: Yaling Liu, Huigang Shu, Ping Wan, Xiaodong Wang and Hong Xie
    Citation: BMC Gastroenterology 2023 23:237
  18. During the COVID-19 pandemic, most of the endoscopic services were electively postponed or suspended. We aimed to assess the safety of a triage policy in patients receiving esophageal variceal ligation during ...

    Authors: Yu-Jen Chen, Ming-Chih Hou, Tsung-Chieh Yang, Pei-Chang Lee, Yi-Hsiang Huang and Fa-Yauh Lee
    Citation: BMC Gastroenterology 2023 23:236
  19. This study was performed to compare a metal stent (MS) and plastic stent (PS) in terms of efficacy and complications during neoadjuvant therapy (NAT) and the perioperative period.

    Authors: Yunxiao Lyu, Shenjian Ye and Bin Wang
    Citation: BMC Gastroenterology 2023 23:235
  20.  Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset, rapid progression, and poor prognosis. Immunotherapy is a first-line trea...

    Authors: Rui Hu, Wei Zhang, Zhiyi Han, Mengqing Ma, Qi Huang, Minling Lv, Wenfeng Ma, Xinfeng Sun, Wenxing Feng, Jing Li, Xin Zhong, Jialing Sun, Wei Yao and Xiaozhou Zhou
    Citation: BMC Gastroenterology 2023 23:234
  21. There is still no consensus on the preferred endoscopic therapy for small bowel angioectasias (SBAs). The aim of this study was to evaluate effectiveness and safety of endoscopic injection sclerotherapy (EIS) ...

    Authors: Jing Yang, Lei Zhou, Dan Xu, Yan Fan and Heng Zhang
    Citation: BMC Gastroenterology 2023 23:233

    The Correction to this article has been published in BMC Gastroenterology 2023 23:330

  22. Helicobacter pylori infection and associated diseases are a growing global public health issue. H. pylori infection is the major cause of gastric cancer, over 90% of duodenal ulcers, and over 70% of gastric ulcer...

    Authors: ShaoWei Han, ZiJie Deng, KaShing Cheung, Tao Lyu, PuiLing Chan, Ying Li, Li Ni, XiaPeng Luo and Kuan Li
    Citation: BMC Gastroenterology 2023 23:231
  23. In Italy, the incidence of SARS-CoV-2 infection peaked in April and November 2020, defining two pandemic waves of coronavirus disease 2019 (COVID-19). This study compared the characteristics and outcomes of pa...

    Authors: Cristina Bezzio, Marta Vernero, Stefania Costa, Alessandro Armuzzi, Gionata Fiorino, Sandro Ardizzone, Jenny Roselli, Sonia Carparelli, Ambrogio Orlando, Flavio Andrea Caprioli, Fabiana Castiglione, Chiara Viganò, Davide G. Ribaldone, Fabiana Zingone, Rita Monterubbianesi, Nicola Imperatore…
    Citation: BMC Gastroenterology 2023 23:230
  24. Probiotics are effective for treating acute infectious diarrhoea caused by bacteria, but there are inconsistent results for the effectiveness of probiotics for diarrhoea caused by viruses. In this article we w...

    Authors: Marcela AG Salazar-Parra, Roberto U Cruz-Neri, Xóchitl AR Trujillo-Trujillo, Juan J Dominguez-Mora, Héctor I Cruz-Neri, Jazmín M Guzmán-Díaz, Mario J Guzmán-Ruvalcaba, Jesús O Vega-Gastelum, Kriscia V Ascencio-Díaz, Maria F Zarate-Casas, Fanny Y González-Ponce, Francisco J Barbosa-Camacho, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Guillermo Alonso Cervantes-Cardona…
    Citation: BMC Gastroenterology 2023 23:229
  25. Endometriosis and irritable bowel syndrome (IBS) have similar symptoms, pathogenesis, and risk factors. These diagnoses often coexist and are frequently misdiagnosed leading to diagnostic delays. This study of...

    Authors: Sofie Stark Junkka and Bodil Ohlsson
    Citation: BMC Gastroenterology 2023 23:228
  26. Liver cirrhosis is a worldwide burden and is associated with poor clinical outcomes, including increased mortality. The beneficial effects of dietary modifications in reducing morbidity and mortality are inevi...

    Authors: Ghazal Daftari, Asal Neshatbini Tehrani, Fereshteh Pashayee-khamene, Sara Karimi, Saleheh Ahmadzadeh, Azita Hekmatdoost, Amin Salehpour, Mahdi Saber-Firoozi, Behzad Hatami and Zahra Yari
    Citation: BMC Gastroenterology 2023 23:227
  27. Esophageal stricture is a common complication after endoscopic submucosal dissection (ESD) for superficial esophageal cancer and precancerous lesions, we intend to investigate the independent risk factors of e...

    Authors: Zhao Mu, Xiao Tang, Jingting Wang, Yulin Chen, Kui Cui, Xingyu Rao, Juan Li and Guodong Yang
    Citation: BMC Gastroenterology 2023 23:226
  28. Recent trials suggested that the Crohn’s disease (CD) exclusion diet (CDED) plus partial enteral nutrition (PEN) is a safe and effective strategy in remission induction of paediatric-onset CD. However, real-wo...

    Authors: María Clara Jijón Andrade, Gemma Pujol Muncunill, Ana Lozano Ruf, Laura Álvarez Carnero, Victor Vila Miravet, Dolores García Arenas, Natalia Egea Castillo and Javier Martín de Carpi
    Citation: BMC Gastroenterology 2023 23:225
  29. Since hepatitis B surface antigen (HBsAg) loss is rarely achieved with nucleos(t)ide analog (NA) treatment, most patients require life-long NA treatment. Previous studies have shown that some patients remain v...

    Authors: Yandi Xie, Minghui Li, Xiaojuan Ou, Sujun Zheng, Yinjie Gao, Xiaoyuan Xu, Ying Yang, Anlin Ma, Jia Li, Yuemin Nan, Huanwei Zheng, Juan Liu, Lai Wei and Bo Feng
    Citation: BMC Gastroenterology 2023 23:224
  30. The Asia-Pacific Colorectal Screening (APCS) score and its derivatives have been used to predict advanced colorectal neoplasia (ACN). However, it remains unknown whether they apply to the current Chinese popul...

    Authors: Chenchen Zhang, Liting Zhang, Weihao Zhang, Bingxin Guan and Shuai Li
    Citation: BMC Gastroenterology 2023 23:223
  31. Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a new classification system for fatty liver disease. In this study, we investigated the clinical characteristics of patients with MAFLD-h...

    Authors: Yusuke Johira, Takashi Nakahara, Takahiro Kinami, Shintaro Yamasaki, Masanari Kosaka, Yuki Shirane, Ryoichi Miura, Serami Murakami, Shigeki Yano, Kei Amioka, Kensuke Naruto, Yuwa Ando, Yumi Kosaka, Kenichiro Kodama, Shinsuke Uchikawa, Hatsue Fujino…
    Citation: BMC Gastroenterology 2023 23:222
  32. Ulcerative colitis is one of the two main forms of inflammatory bowel disease. Cuproptosis is reported to be a novel mode of cell death.

    Authors: Yunfei Pu, Xianzhi Meng and Zhichen Zou
    Citation: BMC Gastroenterology 2023 23:221

    The Correction to this article has been published in BMC Gastroenterology 2023 23:261

  33. Limited research exists on the laboratory characteristics of coexistent primary biliary cholangitis (PBC) and Sjögren’s syndrome (SS). This study aimed to investigate the laboratory risk factors for the coexis...

    Authors: Xuan Gao, Guangzhi Xiao, Fengfan Yang, Rongrong Dou, Miao Xue, Yingying Zhang, Zhaohui Zheng and Jin Ding
    Citation: BMC Gastroenterology 2023 23:220
  34. The optimal timing of endoscopy in liver cirrhosis with acute variceal bleeding (AVB) remains controversial in current guidelines and studies.

    Authors: Mengyuan Peng, Zhaohui Bai, Deli Zou, Shixue Xu, Chunmei Wang, Metin Başaranoğlu, Cyriac Abby Philips, Xiaozhong Guo, Xiaodong Shao and Xingshun Qi
    Citation: BMC Gastroenterology 2023 23:219
  35. Hepatorenal syndrome (HRS) is a life-threatening complication of end-stage liver disease. This study aimed to clarify the status of HRS in Japan by analyzing the Japanese Diagnosis Procedure Combination database.

    Authors: Kazuya Okushin, Hayato Yamana, Ryosuke Tateishi, Masaya Sato, Takeya Tsutsumi, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Kazuhiko Koike and Mitsuhiro Fujishiro
    Citation: BMC Gastroenterology 2023 23:218
  36. N6-methyladenosine (m6A) is associated with mammalian mRNA biogenesis, decay, translation and metabolism, and also contributes greatly to gastrointestinal tumor formation and development. Therefore, the specif...

    Authors: Zhijin Zhang, Jun Fu, Yuhao Zhang, Xianju Qin, Yuexia Wang and Chungen Xing
    Citation: BMC Gastroenterology 2023 23:217
  37. Hepatocellular carcinoma (HCC) is a long-term malignancy that causes high morbidities and mortalities worldwide. Notably, long non-coding RNAs (LncRNAs) have been identified as candidate targets for malignancy...

    Authors: Xiang-Kun Wang, Xu-Dong Zhang, Kai Luo, Long Yu, Shuai Huang, Zhong-Yuan Liu and Ren-Feng Li
    Citation: BMC Gastroenterology 2023 23:216
  38. Fecal incontinence (FI) is caused by external anal sphincter injury. Vitamin E is a potential strategy for anal sphincter muscle repair via its antioxidant, anti-inflammatory, anti-fibrotic, and protective pro...

    Authors: Arash Sarveazad, Abazar Yari, Farnad Imani, Farimah Fayyaz, Marjan Mokhtare, Arash Babaei-Ghazani, Mahmoud Yousefifard, Shahriar Sarveazad, Siavash Assar, Jebreil Shamseddin and Mansour Bahardoust
    Citation: BMC Gastroenterology 2023 23:209
  39. Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer suppor...

    Authors: Yohei Iimura, Mitsuko Nakazawa, Yukari Tsuru, Hitomi Togashi, Tomoe Honda, Keisuke Baba, Masaaki Ishibashi, Chieko Sasuga, Naoki Furukawa, Tomoko Sato, Yasuo Matsubara, Ayako Kamisato, Eiko Yoshii, Seiichiro Kuroda and Narikazu Boku
    Citation: BMC Gastroenterology 2023 23:215
  40. The sole presence of deep submucosal invasion is shown to be associated with a limited risk of lymph node metastasis. This justifies a local excision of suspected deep submucosal invasive colon carcinomas (T1 ...

    Authors: Julia Hanevelt, Jelle F. Huisman, Laura W. Leicher, Miangela M. Lacle, Milan C. Richir, Paul Didden, Joost M. J. Geesing, Niels Smakman, Jochim S. Terhaar Sive Droste, Frank ter Borg, A. Koen Talsma, Ruud W. M. Schrauwen, Bob J. van Wely, Ingrid Schot, Maarten Vermaas, Philip Bos…
    Citation: BMC Gastroenterology 2023 23:214

    The Correction to this article has been published in BMC Gastroenterology 2023 23:256

  41. Colonoscopy is considered the most effective screening method for colorectal polyps. However, the longevity and complexity of the procedure makes it less desirable to screen for colorectal polyps in the genera...

    Authors: Zhang Shao-hua, Ren Lin-lin, Su Shen, Tang Yun-he, Tian Zi-bin, Liu Yi and Mao Tao
    Citation: BMC Gastroenterology 2023 23:213
  42. In metastatic pancreatic ductal adenocarcinoma (mPDAC), first line treatment options usually include combination regimens of folinic acid, 5-fluorouracil (5-FU), irinotecan, and oxaliplatin (FOLFIRINOX or mFOL...

    Authors: Fausto Petrelli, Alessandro Parisi, Gianluca Tomasello, Emanuele Mini, Marcella Arru, Alessandro Russo, Ornella Garrone, Shelize Khakoo, Raffaele Ardito and Michele Ghidini
    Citation: BMC Gastroenterology 2023 23:212

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