Table 1 Univariate and multivariate analysis of clinicopathologic variables in relation to OS in patients living with HIV for GC

Gender

 Female

Reference

 Male

0(0-Inf)

0.998

Age

0.973(0.915–1.033)

0.368

BMI

0.763(0.634–0.918)

0.004

0.799(0.59–1.082)

0.147

Hypertension

 Yes

0.408(0.094–1.771)

0.231

DM

 Yes

1.497(0.496–4.52)

0.474

TB

 Yes

0.962(0.127–7.268)

0.97

Smoking

 Yes

0.195(0.026–1.461)

0.112

Alcohol abuse

 Yes

0.44(0.059–3.31)

0.425

Hyperlipidemia

 Yes

0.763(0.222–2.622)

0.668

Duration of HIV infection

1.001(0.988–1.014)

0.877

Duration of HIV treatment

1.001(0.988–1.014)

0.882

Tumor Location

 Upper

Reference

 Middle

0.892(0.256–3.111)

0.858

 Lower

1.609(0.267–9.696)

0.604

Histology

 Signet ring cell

5.227(2.013–13.573)

 < 0.001

41.178(6.287–269.722)

 < 0.001

R0 rescetion

 No

5.204(1.678–16.141)

0.004

277.461(10.475–7349.318)

 < 0.001

Her2 status

 0

Reference

 1 + 

0.728(0.273–1.941)

0.525

 2 + 

0.256(0.033–1.977)

0.192

AJCC stage

 I-II

Reference

Reference

 III-IV

6.199(1.922–19.996)

0.002

0.314(0.034–2.867)

0.305

ALB (g/L)

 > 38.1

Reference

Reference

 ≤ 38.1

4.192(1.599–10.991)

0.004

10.715(0.632–181.541)

0.1

CD8 count (per ul)

 > 661

Reference

 ≤ 661

0.603(0.24–1.514)

0.281

CD4 count (per ul)

 > 348

Reference

 ≤ 348

2.646(0.943–7.425)

0.065

CD4/CD8

 > 0.71

Reference

 ≤ 0.71

2.062(0.738–5.762)

0.167

NLR

 > 3.9

Reference

 ≤ 3.9

0.416(0.157–1.102)

0.078

LMR

 > 6.5

Reference

 ≤ 6.5

3.325(0.442–24.99)

0.243

PLR

 > 199.0

Reference

Reference

 ≤ 199.0

0.365(0.147–0.903)

0.029

0.038(0.006–0.258)

 < 0.001

PNI

 > 43.4

Reference

Reference

 ≤ 43.4

3.05(1.216–7.653)

0.017

0.261(0.016–4.356)

0.349

SII

 > 935

Reference

 ≤ 935

0.356(0.126–1.006)

0.051

SIS

 0

Reference

 1

0.704(0.198–2.502)

0.587

 2

1.854(0.566–6.074)

0.308