Table 1 Comparison of clinical characteristics between patients with and without osteosarcopenia

Patients, n (%)

126

24 (19.0)

102 (81.0)

Men, n (%)

77 (61.1)

10 (41.7)

67 (65.7)

0.030

Age (years)

70.5 (57.8–76.0)

76.0 (73.0–80.0)

68.0 (56.5–75.0)

0.001

BMI (kg/m²)

23.6 (21.2–25.8)

20.7 (18.7–22.2)

24.1 (22.2–26.2)

 < 0.001

Etiology

 HBV/HCV/Alcohol/other, n

13/36/47/30

1/12/4/7

12/24/43/23

0.022

 Child–Pugh B/C, n (%)

44 (34.9)

6 (25.0)

38 (37.3)

0.257

 MELD score

9.0 (7.0–12.0)

8.0 (7.0–10.0)

9.0 (7.0–12.0)

0.603

 Total bilirubin (mg/dL)

0.9 (0.6–1.3)

0.8 (0.5–1.2)

0.9 (0.7–1.3)

0.212

 Albumin (g/dL)

3.9 (3.4–4.3)

4.0 (3.3–4.4)

3.8 (3.5–4.2)

0.791

 Prothrombin time INR

1.11 (1.04–1.22)

1.07 (1.01–1.13)

1.14 (1.04–1.27)

0.030

 FIB-4

4.16 (2.76–5.57)

4.75 (3.27–5.47)

3.87 (2.74–5.69)

0.441

 M2BPGi (C.O.I)

2.97 (1.47–5.60)

2.59 (1.98–3.54)

3.32 (1.39–6.13)

0.558

SMI (kg/m²)

 All patients

6.76 (5.87–7.52)

5.22 (4.58–5.64)

7.04 (6.33–7.82)

 < 0.001

 Men

7.30 (6.65–8.09)

5.63 (5.25–6.20)

7.38 (6.96–8.16)

 < 0.001

 Women

5.87 (5.07–6.45)

4.78 (4.49–5.23)

6.08 (5.81–6.58)

 < 0.001

Handgrip strength (kg)

 All patients

24.5 (16.7–31.9)

14.5 (12.6–18.0)

28.3 (21.0–34.5)

 < 0.001

 Men

30.7 (24.9–36.7)

20.5 (13.0–24.9)

31.6 (28.1–37.4)

 < 0.001

 Women

16.5 (13.8–21.7)

14.3 (10.1–15.7)

19.1 (14.6–22.5)

 < 0.001

Slow gait speed, n (%)

36 (28.6)

15 (62.5)

21 (20.6)

 < 0.001

Lumbar spine BMD (kg/m²)

1.09 (0.90–1.23)

0.90 (0.83–0.99)

1.16 (0.95–1.26)

 < 0.001

Femoral neck BMD (kg/m²)

0.79 (0.65–0.90)

0.60 (0.53–0.65)

0.83 (0.72–0.93)

 < 0.001

Total hip BMD (kg/m²)

0.83 (0.71–0.96)

0.63 (0.55–0.71)

0.87 (0.77–0.98)

 < 0.001

BCAA supplementation, n (%)

25 (19.8)

2 (8.3)

23 (22.5)

0.116