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  1. Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Hedgehog Interacting Protein (HHIP) is evolutionarily conserved protein, which are important morphogens for a wide range of developm...

    Authors: Fengyihuan Fu, Yuan Zhang, Jubin Feng and Yuqiang Nie
    Citation: BMC Gastroenterology 2023 23:278
  2. This study aimed to evaluate the predictive value of computed tomography (CT) texture features in the treatment response of patients with advanced pancreatic cancer (APC) receiving palliative chemotherapy.

    Authors: Jingjing Li, Jiadi Du, Yuying Li, Mingzhu Meng, Junjie Hang and Haifeng Shi
    Citation: BMC Gastroenterology 2023 23:274
  3. The purpose of this study was to investigate the differences between the clinical characteristics and the factors influencing liver injury in patients with the Omicron subvariant BA.5.2 (Omicron BA.5.2) and th...

    Authors: Jie Li, Qing Zhang, Chao Xu, Yan Zhang, Yueyue Lu, Minghua Ai and Xiaoping Tan
    Citation: BMC Gastroenterology 2023 23:271
  4. Colorectal cancer (CRC) is one of the most common malignancies in the world. This study proposes to reveal prognostic biomarkers for the prognosis and treatment of CRC patients.

    Authors: Chengxing Wang, Yaoming He, Yu He, Weijun Liang, Chaorong Zhou, Meimei Wu, Zijie Meng, Wanglin Li and Jie Cao
    Citation: BMC Gastroenterology 2023 23:270
  5. Gastroesophageal reflux disease (GERD) is a common digestive problem in adults particularly medical students, who are one of the most vulnerable groups. Many variables, including lifestyle changes and psycholo...

    Authors: Mohamed Baklola, Mohamed Terra, Amr Badr, Fayrouz Mohamed Fahmy, Enas Elshabrawy, Yousef Hawas, Doaa Abdel-Hady and Abdel-Hady El-Gilany
    Citation: BMC Gastroenterology 2023 23:269
  6. We read the comments by Nylund K et al. regarding our paper “Ultrasonographic scores for ileal Crohn’s disease assessment: Better, worse or the same as contrast‑enhanced ultrasound?”. Intestinal ultrasound has...

    Authors: Marta Freitas, Francisca Dias de Castro, Vítor Macedo Silva, Cátia Arieira, Tiago Cúrdia Gonçalves, Sílvia Leite, Maria João Moreira and José Cotter
    Citation: BMC Gastroenterology 2023 23:266

    The original article was published in BMC Gastroenterology 2023 23:265

  7. We read with interest the study by Freitas et al. comparing contrast-enhanced ultrasound (CEUS) and parameters from a time-intensity curve (TIC) with the SUS-CD score and IBUS-SAS score in patients with Crohn’...

    Authors: Kim Nylund, Kerri Novak and Rune Wilkens
    Citation: BMC Gastroenterology 2023 23:265

    The original article was published in BMC Gastroenterology 2022 22:252

    The Matters Arising to this article has been published in BMC Gastroenterology 2023 23:266

  8. Structural maintenance of chromosomes protein 1 A (SMC1A) is a crucial subunit of the cohesion protein complex and plays a vital role in cell cycle regulation, genomic stability maintenance, chromosome dynamic...

    Authors: Yaling Liu, Xianrui Fang, Qianqian Wang, Da Xiao, Ting Zhou, Kuo Kang, Zhenyu Peng, Feng Ren and Jingyu Zhou
    Citation: BMC Gastroenterology 2023 23:268
  9. Hepatocellular carcinoma (HCC) with bile duct invasion (BDI) (BDIHCC) has a poor prognosis. Moreover, due to the paucity of reports, there is no consensus regarding optimal management of this clinical conditio...

    Authors: Takashi Iizumi, Toshiyuki Okumura, Naoyuki Hasegawa, Kazunori Ishige, Kuniaki Fukuda, Emiko Seo, Hirokazu Makishima, Hikaru Niitsu, Mizuki Takahashi, Yuta Sekino, Hiroaki Takahashi, Daichi Takizawa, Yoshiko Oshiro, Keiichiro Baba, Motohiro Murakami, Takashi Saito…
    Citation: BMC Gastroenterology 2023 23:267
  10. Mild acute biliary pancreatitis (MABP) is one of the most common diseases that require surgical treatment. Previous studies have focused on the timing of laparoscopic cholecystectomy (LC) for MABP. However, th...

    Authors: Hao Cai, Jian Du, Cheng Luo and Shengwei Li
    Citation: BMC Gastroenterology 2023 23:264
  11. The effectiveness of chemotherapy in older adult patients with biliary tract cancer (BTC) remains to be established, despite the fact that the majority of patients diagnosed with BTC tend to be aged ≥ 70 years...

    Authors: Takeru Hirao, Kenji Ikezawa, Toshitaka Morishima, Kazuma Daiku, Yusuke Seiki, Ko Watsuji, Yasuharu Kawamoto, Sena Higashi, Makiko Urabe, Yugo Kai, Ryoji Takada, Takuo Yamai, Kaori Mukai, Tasuku Nakabori, Hiroyuki Uehara, Isao Miyashiro…
    Citation: BMC Gastroenterology 2023 23:263
  12. A considerable number of patients with colon cancer present with a colonic obstruction. The use of self-expanding metallic stents (SEMS) as a bridge to surgery (BTS) in potential curative patients with left-si...

    Authors: Noura S Alhassan, Sulaiman A AlShammari, Razan N AlRabah, Amirah M AlZahrani, Maha-Hamadien Abdulla, Thamer A Bin Traiki, Ahmad M Zubaidi, Omar A Al-Obeed and Khayal A Alkhayal
    Citation: BMC Gastroenterology 2023 23:262
  13. The methylation SEPT9 (mSEPT9) appeared to be effective for hepatocellular carcinoma (HCC) detection. However, its performance in high-risk population has not been validated. We designed a pilot study and aime...

    Authors: Kepu Zheng, Leiyang Dai, Yingpeng Zhao, Laibang Li, Wang Li, Xibing Zhang, Qiuming Su, Ruichao Wu, Yizhou Jiang, Yonglin Chen and Jianghua Ran
    Citation: BMC Gastroenterology 2023 23:260
  14. N6A methylation (m6A) is a significant epigenetic modification that critically impacts post-transcriptional regulation and tumor occurrence and development. While previous studies have identified a role for ep...

    Authors: Zhen Zhang, Wenhui Gao, Zhuo Liu, Shuxian Yu, Huiying Jian, Zongwei Hou and Puhua Zeng
    Citation: BMC Gastroenterology 2023 23:259
  15. Crohn’s diseases and ulcerative colitis, both of which are chronic immune-mediated disorders of the gastrointestinal tract are major contributors to the overarching Inflammatory bowel diseases. It has become i...

    Authors: Raed M. Alsulaiman, Abdulaziz A. Al-Quorain, Fahad A. Al-Muhanna, Stanley Piotrowski, Ezzeddin A. Kurdi, Chittibabu Vatte, Ahmed A. Alquorain, Noorah H. Alfaraj, Abdulaziz M. Alrezuk, Fred Robinson, Alexa K. Dowdell, Turki A. Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla…
    Citation: BMC Gastroenterology 2023 23:258
  16. Authors: Julia Hanevelt, Jelle F. Huisman, Laura W. Leicher, Miangela M. Lacle, Milan C. Richir, Paul Didden, Joost M. J. Geesing, Niels Smakman, Jochim S. Terhaar Sive Droste, Frank ter Borg, A. Koen Talsma, Ruud W. M. Schrauwen, Bob J. van Wely, Ingrid Schot, Maarten Vermaas, Philip Bos…
    Citation: BMC Gastroenterology 2023 23:256

    The original article was published in BMC Gastroenterology 2023 23:214

  17. Patients with inflammatory bowel disease report multiple symptoms, but the relationships among co-occurring symptoms are poorly understood. This study aimed to examine the prevalence of symptoms and explore sy...

    Authors: Ingunn Johansen, Milada Cvancarova Småstuen, Stine Torp Løkkeberg, Vendel Ailin Kristensen, Marte Lie Høivik, Charlotte Lund, Bjørn Olsen, Vibeke Strande, Gert Huppertz-Hauss, Tone Bergene Aabrekk, May-Bente Bengtson, Petr Ricanek, Trond Espen Detlie, Svein Oskar Frigstad, Lars-Petter Jelsness-Jørgensen and Randi Opheim
    Citation: BMC Gastroenterology 2023 23:255
  18. Gallstone disease poses a significant health burden in the United States. Choledocholithiasis and cholangitis are common complications of gallstone disease for which data on current epidemiological trends are ...

    Authors: Suqing Li, Leonardo Guizzetti, Christopher Ma, Abdel Aziz Shaheen, Elijah Dixon, Chad Ball, Sachin Wani and Nauzer Forbes
    Citation: BMC Gastroenterology 2023 23:254
  19. Periampullary diverticulum (PAD) may make the performance of endoscopic retrograde cholangiopancreatography (ERCP) in patients with choledocholithiasis more difficult and may increase complication rates. The p...

    Authors: He-xian Shi, Yong-qiang Ye, Hai-wang Zhao, De-cai Kong, Shan-zhou Huang, Qian Yan, Yu-bin Chen, Ping Zhang, Sheng Chen, Bao-hua Hou and Chuan-zhao Zhang
    Citation: BMC Gastroenterology 2023 23:252
  20. Colonic self-expandable metallic stent (SEMS) placement enables preoperative total colonoscopy (TCS) in patients with obstructive colorectal cancer. Following SEMS placement, it is possible to assess the prese...

    Authors: Shuichi Itonaga, Shohei Hamada, Eikichi Ihara, Hitoshi Honma, Hiroki Fukuya, Akito Ookubo, Taisuke Sasaki, Daisuke Yoshimura, Makoto Nakamuta, Yorinobu Sumida and Naohiko Harada
    Citation: BMC Gastroenterology 2023 23:251
  21. Platelet (PLT) transfusion was the most practical way to increase patients’ PLT counts before invasive hepatic procedures such as radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). A novel drug ...

    Authors: Hideo Yoshida, Takamasa Ohki, Mineo Kanezaki, Takuma Teratani, Shinpei Sato, Shuntaro Obi, Takahisa Sato, Masatoshi Akamatsu, Koji Uchino and Hiroyoshi Taniguchi
    Citation: BMC Gastroenterology 2023 23:250
  22. This study aimed to evaluate the efficacy, adverse events, patient compliance, and cost of dual therapy with Ilaprazole-amoxicillin (IA) at high dose versus Ilaprazole-amoxicillin-furazolidone-bismuth (IAFB) q...

    Authors: Xiao-Dong Zhang, Da-Ya Zhang, Run-Xiang Chen, Shi-Ju Chen, Chen Chen, Fan Zeng, Shi-Mei Huang, Da Li and Fei-Hu Bai
    Citation: BMC Gastroenterology 2023 23:249
  23. Gastrointestinal Tuberculosis (GITB) and Crohn’s disease (CD) are both chronic granulomatous diseases with a predilection to involve primarily the terminal ileum. GITB is often considered a disease of the deve...

    Authors: Arup Choudhury, Jasdeep Dhillon, Aravind Sekar, Pankaj Gupta, Harjeet Singh and Vishal Sharma
    Citation: BMC Gastroenterology 2023 23:246
  24. Some patients with Crohn’s disease report posttraumatic growth, which can promote reductions in anxiety and depression, and improve the patient’s quality of life. However, the process of posttraumatic growth r...

    Authors: Ying Wang, Chen Zhang and Yunxian Zhou
    Citation: BMC Gastroenterology 2023 23:244
  25. Gastric anisakiasis typically causes severe abdominal symptoms; however, we incidentally detected asymptomatic gastric anisakiasis cases during esophagogastroduodenoscopy. The factors associated with developin...

    Authors: Yutaka Okagawa, Tetsuya Sumiyoshi, Takayuki Imagawa, Hiroya Sakano, Fumito Tamura, Yohei Arihara, Yusuke Kanari, Akira Sakurada, Shutaro Oiwa, Takashi Jin, Yusuke Tomita, Shinya Minami, Hiroyuki Hisai, Hirohito Muramatsu, Shinichi Katsuki, Masahiro Maeda…
    Citation: BMC Gastroenterology 2023 23:243
  26. Vertical transmission of hepatitis C virus (HCV) is the primary cause of hepatitis C in the pediatric population. Nonetheless, only a small proportion of HCV-exposed children are tested. This study aimed to me...

    Authors: Ndeye Licka Dieye, Mine Varol, Shauna C. Zorich, Amy E. Millen, Karl O. A. Yu and Oscar G. Gómez-Duarte
    Citation: BMC Gastroenterology 2023 23:242
  27. Thiopurines continue to play an important role in the treatment of inflammatory bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. Especially, hematopoietic toxicity ma...

    Authors: Shizuka Suzuki, Kan Uchiyama, Yutaro Motoi, Yuuki Yoshii, Yukari Inoue, Takahiro Kubota, Shunichi Odahara, Yuichiro Ohtaki, Shinichiro Takami, Zensho Ito, Nobuhiro Sato, Toshifumi Ohkusa, Shigeo Koido and Masayuki Saruta
    Citation: BMC Gastroenterology 2023 23:239
  28. Gastric neuroendocrine carcinoma (GNEC) is a rare histology of gastric cancer. The retrospective study was designed to construct and validate a nomogram for predicting the cancer-specific survival (CSS) of pos...

    Authors: Xue Song, Yangyang Xie and Yafang Lou
    Citation: BMC Gastroenterology 2023 23:238
  29. Parental liver transplantation (PLT) improves long-term survival rates in paediatric hepatic failure patients; however, the mechanism of PLT-induced postoperative pulmonary complications (PPCs) is unclear.

    Authors: Yaling Liu, Huigang Shu, Ping Wan, Xiaodong Wang and Hong Xie
    Citation: BMC Gastroenterology 2023 23:237
  30. During the COVID-19 pandemic, most of the endoscopic services were electively postponed or suspended. We aimed to assess the safety of a triage policy in patients receiving esophageal variceal ligation during ...

    Authors: Yu-Jen Chen, Ming-Chih Hou, Tsung-Chieh Yang, Pei-Chang Lee, Yi-Hsiang Huang and Fa-Yauh Lee
    Citation: BMC Gastroenterology 2023 23:236
  31. This study was performed to compare a metal stent (MS) and plastic stent (PS) in terms of efficacy and complications during neoadjuvant therapy (NAT) and the perioperative period.

    Authors: Yunxiao Lyu, Shenjian Ye and Bin Wang
    Citation: BMC Gastroenterology 2023 23:235
  32.  Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset, rapid progression, and poor prognosis. Immunotherapy is a first-line trea...

    Authors: Rui Hu, Wei Zhang, Zhiyi Han, Mengqing Ma, Qi Huang, Minling Lv, Wenfeng Ma, Xinfeng Sun, Wenxing Feng, Jing Li, Xin Zhong, Jialing Sun, Wei Yao and Xiaozhou Zhou
    Citation: BMC Gastroenterology 2023 23:234
  33. There is still no consensus on the preferred endoscopic therapy for small bowel angioectasias (SBAs). The aim of this study was to evaluate effectiveness and safety of endoscopic injection sclerotherapy (EIS) ...

    Authors: Jing Yang, Lei Zhou, Dan Xu, Yan Fan and Heng Zhang
    Citation: BMC Gastroenterology 2023 23:233

    The Correction to this article has been published in BMC Gastroenterology 2023 23:330

  34. Helicobacter pylori infection and associated diseases are a growing global public health issue. H. pylori infection is the major cause of gastric cancer, over 90% of duodenal ulcers, and over 70% of gastric ulcer...

    Authors: ShaoWei Han, ZiJie Deng, KaShing Cheung, Tao Lyu, PuiLing Chan, Ying Li, Li Ni, XiaPeng Luo and Kuan Li
    Citation: BMC Gastroenterology 2023 23:231
  35. In Italy, the incidence of SARS-CoV-2 infection peaked in April and November 2020, defining two pandemic waves of coronavirus disease 2019 (COVID-19). This study compared the characteristics and outcomes of pa...

    Authors: Cristina Bezzio, Marta Vernero, Stefania Costa, Alessandro Armuzzi, Gionata Fiorino, Sandro Ardizzone, Jenny Roselli, Sonia Carparelli, Ambrogio Orlando, Flavio Andrea Caprioli, Fabiana Castiglione, Chiara Viganò, Davide G. Ribaldone, Fabiana Zingone, Rita Monterubbianesi, Nicola Imperatore…
    Citation: BMC Gastroenterology 2023 23:230
  36. Probiotics are effective for treating acute infectious diarrhoea caused by bacteria, but there are inconsistent results for the effectiveness of probiotics for diarrhoea caused by viruses. In this article we w...

    Authors: Marcela AG Salazar-Parra, Roberto U Cruz-Neri, Xóchitl AR Trujillo-Trujillo, Juan J Dominguez-Mora, Héctor I Cruz-Neri, Jazmín M Guzmán-Díaz, Mario J Guzmán-Ruvalcaba, Jesús O Vega-Gastelum, Kriscia V Ascencio-Díaz, Maria F Zarate-Casas, Fanny Y González-Ponce, Francisco J Barbosa-Camacho, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Guillermo Alonso Cervantes-Cardona…
    Citation: BMC Gastroenterology 2023 23:229
  37. Endometriosis and irritable bowel syndrome (IBS) have similar symptoms, pathogenesis, and risk factors. These diagnoses often coexist and are frequently misdiagnosed leading to diagnostic delays. This study of...

    Authors: Sofie Stark Junkka and Bodil Ohlsson
    Citation: BMC Gastroenterology 2023 23:228

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